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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T77092 | Nadecnemab | REGN-5069 | Others |
Nadecnemab is an IGG4-κantibody targeting GFRA3, a receptor of the glial cell-derived neurotrophic factor family. Nadecnemab can be used for knee osteoarthritis and neurological disorders. | |||
T10624 | BT-13 | c-RET | |
BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro. | |||
T13587 | BT18 | Others | |
BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function. | |||
T71576 | SIM010603 | ||
SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived g... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293) | Human | HEK293 |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact... | |||
TMPY-04535 | GDNF Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact... | |||
TMPY-02911 | GDNF Protein, Rat, Recombinant (His) | Rat | Baculovirus-Insect Cells |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact... | |||
TMPY-06970 | GDNF Protein, Human, Recombinant | Human | E. coli |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact... | |||
TMPY-01458 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-01391 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-05490 | GFR Alpha-1/GFRA1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-03894 | GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPJ-00290 | GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two s... | |||
TMPY-03709 | GFR Alpha-1/GFRA1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-02536 | GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-01419 | GFR Alpha-1/GFRA1 Protein, Human, Recombinant (His) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-01088 | GFR Alpha-1/GFRA1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-03714 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-01994 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPK-00109 | Artemin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored... | |||
TMPY-00568 | CDNF Protein, Human, Recombinant (His) | Human | HEK293 |
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril... | |||
TMPY-01916 | CDNF Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril... | |||
TMPY-00188 | CDNF Protein, Human, Recombinant (hFc) | Human | HEK293 |
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril... | |||
TMPY-01440 | GFR Alpha-2/GFRA2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRA2 is a potent ... | |||
TMPY-01420 | GFR Alpha-2/GFRA2 Protein, Human, Recombinant (His) | Human | HEK293 |
GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRA2 is a potent ... | |||
TMPY-01576 | Artemin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored... | |||
TMPJ-01290 | Neurturin Protein, Human, Recombinant | Human | E. coli |
Neurturin is a member of the GDNF family of ligands, which include glial cell-derived neurotrophic factor (GDNF), Neurturin, Persephin, and Artemin. Neurturin is expressed in both neuronal and nonneuronal tissues. Simila... | |||
TMPY-02270 | RET Protein, Human, Recombinant (His) | Human | HEK293 |
RET proto-oncogene, also known as RET, is a cell-surface molecule that transduce signals for cell growth and differentiation. It contains 1 cadherin domain and 1 protein kinase domain. RET proto-oncogene belongs to the p... | |||
TMPY-04418 | RET Protein, Human, Recombinant (aa 658-1114, His & GST) | Human | Baculovirus-Insect Cells |
RET proto-oncogene, also known as RET, is a cell-surface molecule that transduce signals for cell growth and differentiation. It contains 1 cadherin domain and 1 protein kinase domain. RET proto-oncogene belongs to the p... |